Polycystic ovarian syndrom. Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: Clomiphen 50 mg, 2 per day, 5-7 days. Intervention 2: Tab Metformin 500 mg, 3 per day, 3 month + Clomiphen 50 mg, 2 per day, 5-7 days.
Treatment - Drugs
Clomiphen 50 mg, 2 per day, 5-7 days
Tab Metformin 500 mg, 3 per day, 3 month + Clomiphen 50 mg, 2 per day, 5-7 days
Sponsors
Vice chanceller of Research and Technology of Babol University of medical sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Infertile patients with PCOS. 2. Normal values of TSH and prolactin 3. Normal creatinin level 4. Normal liver function (SGOT, SGPT). Exclusion criteria: 1. hyperprolactinemia 2. thyroid disease 3.endometriosis 4. tubal factor 5. male factor 6. metformin with side effect background 7. diabetes mellitus.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of mature follicle. Timepoint: 12th-16th day of cycle. Method of measurement: transvaginal ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pregnancy. Timepoint: 16 days after IUI (16-18 cycle day). Method of measurement: BHCG Examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMasoumeh Golsorkhtabar Amiri
Fatemeh-Zahra Infertility and Reproductive Health Research Center,Babol University of Medical Scienc
Outcome results
None listed