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Selecting optimized method for ovulation induction

Clomiphene citrate and Letrozole comparison in the treatment of anovulating patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138904154339N1
Enrollment
200
Registered
2011-02-07
Start date
2009-03-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility.

Interventions

Intervention 1: Letrozole 2.5 or 5 or 7.5 mg orally according to setup protocol for 5 days since 3rd day of menstruation cycle in first group. Intervention 2: clomiphene citrate 50 or 100 or 150 mg or
Treatment - Drugs
Letrozole 2.5 or 5 or 7.5 mg orally according to setup protocol for 5 days since 3rd day of menstruation cycle in first group
clomiphene citrate 50 or 100 or 150 mg orally according to setup protocol for 5 days since 3rd day of menstruation cycle in second group

Sponsors

Research managment center of Bushehr University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Infertile anovulating women in reproductive age Exclusion criteria: Any abnormality in thyroid and prolactin tests and structural abnrmalities of uterus and tubes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Adequate follicle. Timepoint: The 13th - 14th day of menstruation cycle. Method of measurement: Vaginal sonography.;Endometrial thickness. Timepoint: The 13th - 14th day of menstruation cycle. Method of measurement: Vaginal sonography.;Estradiol concentration. Timepoint: The 13th - 14th day of menstruation cycle. Method of measurement: Biochemical methods for mesuring estradiol titer.;Pregnancy. Timepoint: 14 days after ovulation. Method of measurement: ßhCG Test.;Alive fetus. Timepoint: The 7th week of pregnancy. Method of measurement: Vaginal sonography.

Secondary

MeasureTime frame
Ovarian cyst. Timepoint: The 13th - 14th day of menstruation cycle. Method of measurement: Vaginal sonography.;Abnormal Uterine Bleeding. Timepoint: During menstruation cycle. Method of measurement: Patients history.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Shahnaz Ahmadi

Bushehr University of Medical Sciences, Medical Faculty

ahmadishahnaz2005@yahoo.com+98 77 1252 4044

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026