Polycystic Ovary Syndrome. Polycystic Ovary Syndrome
Conditions
Interventions
Intervention 1: Intervention Group: Clomiphene Citrate (150mg) plus Tamoxifen (20mg), third day of menstrual cycle for 5 days. Intervention 2: Control group: Standard method including 150 mg of Clomip
Treatment - Drugs
Intervention Group: Clomiphene Citrate (150mg) plus Tamoxifen (20mg), third day of menstrual cycle for 5 days
Control group: Standard method including 150 mg of Clomiphene daily, with Gonadotropin in sixth, seventh and eighth days of menstrual cycle
Sponsors
Vice Chancellor for Research and Technology, Babol University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: PCOS Clomiphen citrate resistance Patients with age between 18 and 35 years, years period of infertility between 1.5-5 yr and BMI between 19-35. Exclusion criteria: hyperprolactinaemia, hypercorticism or thyroidism, pelvic pathology or surgery, infertility factor other than anovulation excluded.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dominant follicle. Timepoint: 12 -16 menstrual cycle. Method of measurement: sonography.;Rate ovulation. Timepoint: 36-38 days after HCG injection. Method of measurement: sonography.;Endometrial thickness. Timepoint: at HCG injection day. Method of measurement: sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of pregnancy. Timepoint: 25 days after HCG injection. Method of measurement: sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNargess Gholizadeh Pasha
Fatemehzahra Fertility & reproductive Health Reseach Center
Outcome results
None listed