Condition 1: Recurrent depressive disorder, unspecified. Condition 2: hypertension. Monopolar depression NOS High blood pressure
Conditions
Interventions
Intervention 1: Interventional group: tab sertraline 50 -100 mg daily for 4 -6 weeks. Intervention 2: Control group: placebo with the same shape, size and taste for 4–6 weeks.
Treatment - Drugs
Placebo
Interventional group: tab sertraline 50 -100 mg daily for 4 -6 weeks
Control group: placebo with the same shape, size and taste for 4–6 weeks
Sponsors
Tabriz medical sience university
Eligibility
Sex/Gender
Female
Age
15 Years to 49 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Sex age, Age 15 – 49 year old, presence of drug resistant hypertension, With PMS (premenstrual syndrome), With written informed consent form Exclusion criteria: history of allergic reaction or side effect with sertaline, BMD (bipolar mood disorder), MDD (major depressive disorder), anxiety disorders, psychosis, cognitive disorders, or mental retardation, Pregnancy, breast feeding, Acute coronary syndromes, Heart failure
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: Before / 4-6 weeks after intervention. Method of measurement: Blood pressure mannometer (mmHg). | — |
Secondary
| Measure | Time frame |
|---|---|
| Sertraline side effect. Timepoint: Weekly. Method of measurement: Antidepressant side effects questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Fatemeh Ranjbar Kouchaksaraie
Tabriz University of Medical Sciences
Outcome results
None listed