Female infertility associated with anovulation. Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: Laparoscopic unilateral ovarian cauterization. Intervention 2: Laparoscopic bilateral ovarian cauterization.
Treatment - Surgery
Laparoscopic unilateral ovarian cauterization
Laparoscopic bilateral ovarian cauterization
Sponsors
Research vice chancellorship-Guilan university of Medical Science
Eligibility
Sex/Gender
Female
Age
20 Years to 38 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age: 20-38, BMI<32, infertile women with polycystic ovarian syndrome and infertility duration more than 1 year caused by disorder of ovulation, normal semen analysis in partner, normal hystrosalpangography, rsistance to Clomiphene citrate, absence of any major disease. Exclusion criteria: Other cause of infertility, use of other indicated ovulation diets like Metformin, any abnormalities of fallopian tubes and endometriosis during laparoscopy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovulation rate. Timepoint: every month up to 6 months. Method of measurement: Observing ovulation signs in serial transvaginal sonography and measuring progesterone level at 21th day of menstrual cycle. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum hormonal level (FSH, LH, testosterone). Timepoint: Third day of first menstrual cycle after laparoscopy. Method of measurement: According to FSH, LH (mIU/ml) and testosterone (nmol/ml).;Clomiphene citrate dose for induction ovulation (If ovulation spontaneously don’t return). Timepoint: 6 weeks and 10 weeks after laparoscopy. Method of measurement: Amount of Clomiphen citrate (mg) needed for ovolation.;Pregnancy rate. Timepoint: during 6 month after laparoscopy. Method of measurement: Observing gestational sac in transvaginal sonography and positive serumal BhCG. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed