Chronic apical periodontitis.
Conditions
Interventions
Intervention 1: Intervention group: After first antimicrobial sampling upon access ( S1), in this group irrigation was carried out with normal saline. Two milliliters of this solution were used to irr
SybronEndo, Orange, CA, USA) using cold lateral compaction technique. The tooth was temporized and permanent restoration was planned at the next visit.Moreover, the patients will follow-up after 30 mo
SybronEndo, Orange, CA, USA) using cold lateral compaction technique. The tooth was temporized and permanent restoration was planned at the next visit. Moreover, the patient will follow-up 30 months a
Treatment - Other
Intervention group: After first antimicrobial sampling upon access ( S1), in this group irrigation was carried out with normal saline. Two milliliters of this solution were used to irrigate the canals
Positive control group: After the first antimicrobial sampling upon access (S1), in this group irrigation was performed with 2 mL 2.5% NaOCl after each instrument (10mL overall).After instrumentation
Sponsors
Shiraz university of Medical Scienced
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Only teeth with necrotic pulps as confirmed by negative response to sensitivity pulp tests were included in this study. Patients who received antibiotic therapy within the past 3 months were excluded from the study. Teeth with extensive caries or with fractures of the root/crown and with history of previous endodontic treatment did not consider in the study. Besides, cases showing periodontal pockets over 4 mm depth were also excluded.In the second phase,presence of sinus tract, swelling, mobility, tenderness to percussion or palpation and probing depth greater than the baseline measures will be recorded by an independent investigator and will serve as exclusion criteria
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bacterial load reduction in post-treatment samples in comparison to initial samples. Timepoint: At the end of trearment session. Method of measurement: Microbial colony forming unit( CFU). | — |
Secondary
| Measure | Time frame |
|---|---|
| Any Change in periapical status from the baseline and presence or absence of clinical sign& symptoms after 30-months. Timepoint: 30-months. Method of measurement: Clinical and radiographical evaluation of treated patient after 30-months. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbbas Abbaszadegan
Faculty of Dentistry,Shiraz Universsity of Medical Sciences
Outcome results
None listed