Condition 1: ventilator associated pneumonia. Condition 2: ventilator associated pneumonia. Pneumonia due to Streptococcus pneumoniae Pneumonia due to staphylococcus
Conditions
Interventions
Intervention 1: In first group, will used chlorhexidine gluconate 0.2% mouthwash, manufactured by pharmaceutical company of drug city (Tehran – Iran).all surfaces of mouth, gingiva, tongue, throat and
In first group, will used chlorhexidine gluconate 0.2% mouthwash, manufactured by pharmaceutical company of drug city (Tehran – Iran).all surfaces of mouth, gingiva, tongue, throat and teeth will be s
In second group, will used persica 10% mouthwash, manufactured by pharmaceutical company of pursina. all surfaces of mouth, gingiva, tongue, throat and teeth will be swapped carefully by 10 cc of mout
In third group, will used normal salin mouthwash. all surfaces of mouth, gingiva, tongue, throat and teeth will be swapped carefully by 10 cc of mouthwashes (normal salin) for 6 minutes. Immediately b
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Age between 15-65 years, Third and fourth day of admission in ICU, Intubation and mechanical ventilation for 3 to 4 days, having NG tube for 3 to 4 Exclusion Criteria: Re-intubation, History of antibiotic therapy before admission, Oral anticoagulation therapy,Respiratory and systemic infection, Autoimmune diseases and malignancies, History of allergy to mouthwash, asthma, allergic rhinitis and dermatitis, History of radiation therapy and immunosuppressive therapy including corticosteroid, Use of any kind of antimicrobial mouthwash within 2 months before admission, Diseases of oral mucosa and severe periodontitis, History of splenectomy and Tonsillectomy , Negative cultures of S.aureus and pneumoccocus before use of mouthwash, Occurrence of any reaction to Mouthwashes
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of colony of S.aureus and pneumoccocus. Timepoint: Immediately before and after using mouthwashes. Method of measurement: CFU(Colony-forming unit). | — |
Secondary
| Measure | Time frame |
|---|---|
| Any reaction to Mouthwashes. Timepoint: after using of mouthwashes. Method of measurement: inspection. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHadi Darvishi Khezri
Mazandaran University Of Medical Sciences
Outcome results
None listed