Subclinicsl Hypothyroidism. Subclinical iodine-deficiency hypothyroidism
Conditions
Interventions
Intervention 1: Levothyroxine 50-75 microgram daily/ orally for 3 months. Intervention 2: Placebo 1/2- 3/4 tab daily/ orally.
Treatment - Drugs
Placebo
Levothyroxine 50-75 microgram daily/ orally for 3 months
Placebo 1/2- 3/4 tab daily/ orally
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
14 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: High TSH with FT4 in normal range Exclusion criteria: receiving levothyroxine, glucocorticoids, asprin, amiodaron, lipid lowering agents, OCP, dopamine antagonist eg. metoclopramide or domperidone in 6 months prior to the study, presence of diabetes mellitus, pregnancy, menopause, age older than 60 years
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Triglyceride. Timepoint: Baseline and 3 months after the intervention. Method of measurement: photometery.;Cholestrol. Timepoint: Baseline and 3 months after the intervention. Method of measurement: photometery.;LDL. Timepoint: Baseline and 3 months after the intervention. Method of measurement: photometery.;HDL. Timepoint: Baseline and 3 months after the intervention. Method of measurement: photometery.;Lp(a). Timepoint: Baseline and 3 months after the intervention. Method of measurement: biochemistry. | — |
Secondary
| Measure | Time frame |
|---|---|
| TSH. Timepoint: Baseline and 3 months after the intervention. Method of measurement: chemiluminescence.;FT4. Timepoint: Baseline and 3 months after the intervention. Method of measurement: chemiluminescence. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Karoon Shahebrahimi
Emam Reza hospital
Outcome results
None listed