Type 2 Diabetes. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Placebo
Intervention Group:Probiotic Yoghurt,300 gr/day,6 weeks
Control Group:Conventional Yoghurt,300 gr/day,6 weeks
Intervention 1: Intervention Group:Probiotic Yoghurt,300 gr/day,6 weeks. Intervention 2: Control Group:Conventional Yoghurt,300 gr/day,6 weeks.
Treatment - Drugs
Sponsors
Tabriz University of Medical Sciences
Iran Dairy Industries Company
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: having type 2 diabetes, 30 to 60 years old, LDL level more than 100 mg/Dl Exclusion criteria: having the renal or hepatic failure, cardiovascular disease, inflammatory bowel disease, thyroid disorders and lactose intolerance, treatment with insulin and taking corticosteroids, NSAIDS, immunosuppressives, cholesterol lowering drugs, multivitamin-mineral and fiber supplements, BMI more than 35 Kg/m2, smoking, pregnancy and lactation, use of multivitamin-mineral and fiber supplements 3 weeks prior to the study, use of antibiotics 1 month the study and during the study, having acute gastrointestinal disorders 1 month prior to the study and during the study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HsCRP. Timepoint: baseline and after 6 weeks. Method of measurement: immunotorbidometry.;Fasting Blood Sugar. Timepoint: baseline and after 6 weeks. Method of measurement: spectrophotometry.;Hemoglobin A1c. Timepoint: baseline and after 6 weeks. Method of measurement: Chromatography.;Insulin. Timepoint: baseline and after 6 weeks. Method of measurement: ELIZA.;HOMA-IR. Timepoint: Baseline and after 6 weeks. Method of measurement: Formula.;Total Cholesterol. Timepoint: Baseline and after 6 weeks. Method of measurement: Spectrophotometry.;Triglyceride. Timepoint: Baseline and after 6 weeks. Method of measurement: Spectrophotometry.;HDL. Timepoint: Baseline and after 6 weeks. Method of measurement: Spectrophotometry.;LDL. Timepoint: Baseline and after 6 weeks. Method of measurement: Friedewald Formula.;Malondialdehyde. Timepoint: Baseline and after 6 weeks. Method of measurement: Spectrophotometry.;Catalase. Timepoint: Baseline and after 6 weeks. Method of measurement: Hugo Aebi Method.;Glutathione peroxidase. Timepoint: Baseline and after 6 weeks. Method of measurement: Spectrophotometry.;Superoxide dismutase. Timepoint: Baseline and after 6 weeks. Method of measurement: Spectrophotometry.;Total Antioxidant Capacity (TAC). Timepoint: Baseline and after 6 weeks. Method of measurement: Spectrophotometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body Mass Index. Timepoint: Baseline and after 6 weeks. Method of measurement: Formula.;Dietary Factors. Timepoint: Baseline and after 6 weeks. Method of measurement: 3-day 24h dietary recalls.;Blood Pressure. Timepoint: Baseline and after 6 weeks. Method of measurement: Sphygmomanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Javad Mohtadi Nia
Faculty of Health and Nutrition, Tabriz University of Medical Sciences
Outcome results
None listed