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The effects of Tramadol, Novafen and Naproxen on post-operative pain following endodontic treatment

The effects of Tramadol, Novafen and Naproxen on post-operative pain following endodontic treatment

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138903194006N2
Enrollment
100
Registered
2010-06-09
Start date
2010-07-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative endodontic pain. Other specified disorders of teeth and supporting structures

Interventions

Treatment - Drugs
Intervention 1: Control: Placebo. Intervention 2: Intervention: group1: Tramadol Tab, 100mg in 6, 12 and 24 hours after root canal treatment. Intervention 3: Intervention group 2: Novafen, 325 mg in 6
Placebo
Intervention: group1: Tramadol Tab, 100mg in 6, 12 and 24 hours after root canal treatment
Intervention group 2: Novafen, 325 mg in 6, 12 and 24 hours after root canal treatment
Intervention group 3: Naproxen Tab, 500 mg in 6, 12, and 24 hours afetr root canal treatment

Sponsors

No sponsers
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: aged between 20-60 years; Patients with moderate to severe pain associated with irreversible pulpitis in single-rooted premolars or anterior teeth. Exclusion criteria: systemic diseases; pregnancy in women; taking any analgesics or other drugs prior to presenting for treatment.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Post operative endodontic pain. Timepoint: before intervention, 6, 12 and 24 hours after treatment. Method of measurement: Visual analogue scale quesionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Paymen Mehrvarzfar

Endodontic Department, Dental School of Tehran Azad University, Tehran, Iran

dr.p.mehrvarzfar@dentaliau.ir, mehrvarzfar@gmail.com+98 912 104 5805

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026