Histologic and Histomorphometric Evaluation of Natix Synthetic Biomaterial in Horizontal Alveolar Ridge Augmentation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138903164106N1

Enrollment

Registered

2010-10-26

Start date

2010-03-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Histologic and histomorphometric analysis of horizontal alveolar ridge augmentation. Other disorders of teeth and supporting structures

Interventions

After reflection of a full-thickness flap for gaining access to the buccal bone of edentulous ridge, Natix biomaterial is mixed with blood and saline and then placed on the area of bone defect. Then t

Treatment - Other

Eligibility

Sex/Gender

All

Age

30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1- Patients ranging from 30 to 50 years old 2- Patients demanding implant treatment in posterior regions of mandibular alveolar ridge 3- Sufficient vertical height of bone in posterior mandibular region with inadequate buccolingual width (width of less than 5 mm and minimum width of 2 mm) 4- Healthy patients 5- Minimum of one augmentation site for each patient requiring implant treatment. Exclusion criteria: 1- Patients having systemic conditions affecting healing such as: Uncontrolled Diabetes, Immune diseases, Systemic or local diseases of bone, history of Alcoholism, Patients taking Immunosuppressive or Anticoagulant medications 2- poor compliance 3- Patients having untreated active periodontal disease 4- Patients unable to maintain oral health status or not interested in maintaining oral health status.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Histologic and Histomorphometric Evaluation of effect of Natix Synthetic Biomaterial in Horizontal Alveolar Ridge Augmentation. Timepoint: 8 months after intervention. Method of measurement: Biopsy specimens are taken from the augmented site by Natix, and are stained with Hematoxilin & Eosin and parameters such as: 1-amount of inflammation 2-existence or inexistence of foreign body reaction (giant cells and granulomatous reactions) 3-Bone vitality (Existence or inexistence of osteocytes in lacunaes) 4-Thickness of bone trabecules 5-Way of contact between bone-biomaterial (existence or inexistence of connective tissue between bone fragments) are analysed.	—

Measure

Time frame

Histologic and Histomorphometric Evaluation of effect of Natix Synthetic Biomaterial in Horizontal Alveolar Ridge Augmentation. Timepoint: 8 months after intervention. Method of measurement: Biopsy specimens are taken from the augmented site by Natix, and are stained with Hematoxilin & Eosin and parameters such as: 1-amount of inflammation 2-existence or inexistence of foreign body reaction (giant cells and granulomatous reactions) 3-Bone vitality (Existence or inexistence of osteocytes in lacunaes) 4-Thickness of bone trabecules 5-Way of contact between bone-biomaterial (existence or inexistence of connective tissue between bone fragments) are analysed.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Javad Mehrani Sabet

Babol University of Medical Sciences, Faculty of Dentistry

j.mehrani@mubabol.ac.ir+98 11 1222 4032

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026