Acute Viral bronchiolitis. Acute bronchiolitis
Conditions
Interventions
Intervention 1: In intervention group, nebulized 3% hypertonic saline 3 cc per 10 min till 3 dose, then countinue Q8h if patient addmited. Intervention 2: In control group, standard treatment with neb
Treatment - Other
In intervention group, nebulized 3% hypertonic saline 3 cc per 10 min till 3 dose, then countinue Q8h if patient addmited.
In control group, standard treatment with nebulized 0.9% saline 3cc Q10 min till 3 dose, then continue Q8h if patient admitted.
Sponsors
Vice Chancellor of Research, Bushehr University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 2 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: a total of infant (2 month to 24 month of age )with mild to moderate bronchiolitis seen in aliasghar tertiary care pediatric center ED in 2008-2010(fall & winter)were randomized to double blind treatment with nebulized salbutamol in either 3% saline or 0.9% saline. bronchiolitis: first or second episodes of respiratory distress with wheezing or sign of viral respiratory tract infections includes RR>60; 38c=T; PR>180 or coryza. Exclusion criteria: pre-exiting cardiac or pulmonary disease; previous diagnosis of asthma or positive familial history of asthma; previous history of prematurity(GA60; 38c=T; PR>180 second or more episodes of respiratoye distress.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in sum of RADI score and YALE clinical score. Timepoint: at first & 30 minute later. Method of measurement: physical examination.;Admission rate. Timepoint: 30 minute. Method of measurement: physical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intravenous fluid use. Timepoint: 14 days. Method of measurement: physical examination.;Length of stay. Timepoint: day of discharge. Method of measurement: physical examination.;Oxygen use. Timepoint: day of discharge. Method of measurement: physical examination.;Remission of cough and wheezing. Timepoint: 1 mounth. Method of measurement: physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Gissou Hatami
Bushehr University of Medical Sciences
Outcome results
None listed