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Loratadine effect on the rate of rehospitalization and recurrent angina in patients with acute coronary syndrome

Evaluation of Loratadine effect on the rate of rehospitalization and recurrent angina in patients with acute coronary syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138903131061N7
Enrollment
200
Registered
2010-07-03
Start date
2009-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute coronary syndrome. Acute ischaemic heart disease, unspecified

Interventions

Intervention 1: Intervention group: Loratadine, oral tablet, 10 mg daily for a one month course + Aspirin, oral tablet 80 mg daily + Metoral, oral tablet 25-50 mg towise in day. Intervention 2: Contro
Treatment - Drugs
Intervention group: Loratadine, oral tablet, 10 mg daily for a one month course + Aspirin, oral tablet 80 mg daily + Metoral, oral tablet 25-50 mg towise in day
Control group: Aspirint oral tablet 80 mg daily + Metoralt oral tablet 25-50 mg towice in day

Sponsors

Rafsanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: class 2 and 3 of Braunwald criteria Exclusion criteria: prior history of hospitalization due to acute coronary syndrome, presence of liver disease, using antihistamines drugs such drugs as Cimetidine, Erythromycin, Clarithromycin, anti-fungal group and Fluoxetine

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Readmission. Timepoint: Baseline, the first, second , third, and fourth week after the intervention. Method of measurement: Visual analog scale of readmission.;Recurrent angina. Timepoint: Baseline, the first, second , third, and fourth week after the intervention. Method of measurement: Descriptive scale of chest pain.

Secondary

MeasureTime frame
Side effects of loratadine. Timepoint: Baseline, the first, second , third, and fourth week after the intervention. Method of measurement: Descriptive scale of symptoms such as headache, insomnia, weakness.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026