To study effect of intratechal standard lidocaine and mixture of lidocaine and pethidine on hemodynamic of patient in open prostatectomy. -
Conditions
Interventions
Intervention 1: In control group all patient received lidocaine 5% intratechally (2 cc)and needle entrance is space L4-L5.Other intervention in two group is same. Intervention 2: In case group all pat
Prevention
In control group all patient received lidocaine 5% intratechally (2 cc)and needle entrance is space L4-L5.Other intervention in two group is same.
In case group all patient received lidocaine 5% pulse pethidine 0/5 mg/kg up to 2 cc intratechally and needle entrance is space L4-L5.Other intervention in two group is same.
Sponsors
Research committee of medical science of bushehr university
Eligibility
Sex/Gender
Male
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: All patient who are candidates for open prostatectomy are eligible to participate in the study. Exclusion criteria: age above 75 and below 45, history of sensitivity to opioid, unwilling to participate and coagulopathy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic change (BP change). Timepoint: pre induction and in minute 1,2,3,5,10,15,20,25,30,45,60,90,120. Method of measurement: NIBP monitoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Temperature change. Timepoint: 60 minute. Method of measurement: Temperature Monitoring.;Post operative nausea and vomiting. Timepoint: 120 minute. Method of measurement: observation.;Post operative pain. Timepoint: 120 minute. Method of measurement: Analogous pain score.;Intra operative blood loss. Timepoint: 120 minute. Method of measurement: observation. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed