Comparison of the effects of dexamethasone and granisetron in the prevention of nausea and vomiting after laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138903033939N1

Enrollment

102

Registered

2010-05-24

Start date

2010-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting. nausea and vomiting following gasterointestinal surgery

Interventions

Intervention 1: Dexamethasone 8mg a single dose 15 minutes before anesthesia induction. Intervention 2: Granisetron 3mg a single dose 15 minutes before anesthesia induction.

Treatment - Drugs

Dexamethasone 8mg a single dose 15 minutes before anesthesia induction

Granisetron 3mg a single dose 15 minutes before anesthesia induction

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18-65 years, candidate for laparoscopic cholecystectomy due to symptomatic gall stone, Exclusion criteria: pregnancy, body mass index more than 30, comorbidity, previous laparatomy, gall bladder empyma, receiving opium or corticosteroid a week prior to operation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Rate of nausea and vomiting. Timepoint: each 6 hours for 3 times. Method of measurement: Asking from the patient.	—

Secondary

Measure	Time frame
Other complications (vertigo, headache, pruritus and sweating). Timepoint: each 6 hours for 3 times. Method of measurement: Asking from the patient.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Ali Hessami

Kermanshah University of Medical Sciences

mahessami@kums.ac.ir+98 83 1427 6314

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026