The effectiveness of sucrose in neonatal pain relief

Comparison The effect of oral sucrose 20%, 30% and 50% on relief of behavioural pain responses caused by vitamin k injection in full term infants

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138902223920N1

Enrollment

120

Registered

2010-06-16

Start date

2010-08-24

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain caused by vitamin k IM injection. Health supervision and care of other healthy infant and child

Interventions

Intervention 1: Sucrose 20%, 1cc oral. Intervention 2: Sucrose 30%, 1cc oral. Intervention 3: Sucrose 50%, 1cc oral. Intervention 4: Sterile Water, 1cc oral.

Placebo

Sucrose 20%, 1cc oral

Sucrose 30%, 1cc oral

Sucrose 50%, 1cc oral

Sterile Water, 1cc oral

Eligibility

Sex/Gender

All

Age

1 Years to 2 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: gestational age 37-42 weeks, weight above 2/5 kg, age 1-2 day, Apgar (first min) >= 7. Exclusion criteria: crying, illness, using Naloxan

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Immediately after injection and 5 minutes later. Method of measurement: Neonatal Infant Pain Scale (NIPS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Morady

Semnan University of Medical Sciences

fatemeh_mrdy@yahoo.com+98 23 1444 6529

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026