bronchopulmonary dysplasia, need for oxygen beyond 28 days of birth. bronchopulmonary dysplasia originating in perinatal period
Conditions
Interventions
Intervention 1: Azithromycin, orally, from 7th day of birth for one week with a single dose of 10 mg/kg/daily and then 5 mg/kg/daily for subsequent week. Intervention 2: Control group: no intervention
Treatment - Drugs
Azithromycin, orally, from 7th day of birth for one week with a single dose of 10 mg/kg/daily and then 5 mg/kg/daily for subsequent week
Control group: no intervention
Sponsors
Pediatric Health Research Center, Tabriz University of Medical Sciences,
Eligibility
Sex/Gender
All
Age
7 Years to 120 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: birth weight less than 1500g, feeding starting before 7 days, parental consent for study Exclusion criteria: major congenital anomalies, congenital heart disease, chromosomal defects, death before 7th day of birth, sign of necrotising enterocolitis before 7th day of birth, severe intraventricular hemorrhage (grade 3 or 4)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of need for oxygen. Timepoint: daily. Method of measurement: days count before O2 discontinue.;Needed FIO2. Timepoint: daily. Method of measurement: oxymeter and blender.;Spo2. Timepoint: daily. Method of measurement: pulseoxymetry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospitalization. Timepoint: days of hospital stay. Method of measurement: time between admission and discharge. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Manizheh Mostafa Gharehbaghi/ Dr Majid Mahaleii
Tabriz University of Medical Sciences
Outcome results
None listed