Comparison of the effects of ephedrine, atropine and mucosal phenylephrine perfusion in preventing hypotension during spinal anesthesia for ceasarean section.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138902213912N1

Enrollment

Registered

2010-06-15

Start date

2006-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Single delivery ceasarean. Single delivery by caesarean section

Interventions

100µgr phenylephrine (mucosal) before spinal anesthesia (single dose)

Intervention 1: 0.5 mg atropine (IV) before spinal anesthesia (single dose). Intervention 2: 5mg ephedrine before spinal anesthesia(single dose). Intervention 3: 100µgr phenylephrine (mucosal) before

Treatment - Drugs

0.5 mg atropine (IV) before spinal anesthesia (single dose)

5mg ephedrine before spinal anesthesia(single dose)

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria consisted of age between 20-40 years, ASAphysical status 1 and 11, single pregnancy, elective ceasarean, gestational age=37weeks and patients satisfaction. Exclusion criteria consisted of hypovolemia, deformity of spinal column, increase of ICP, coaglopathy, infection of skin or soft tissue and unsatisfaction of patient .

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: before spinal anesthesia andevery 5 minutes interval through out the surgery until 30 minutes,therefore at 15minutes interval until 1.5 hourrs after spinal. Method of measurement: palseoxymetery.;Heart rate. Timepoint: before spinal anesthesia andevery 5 minutes interval through out the surgery until 30 minutes,therefore at 15minutes interval until 1.5 hourrs after spinal. Method of measurement: palseoxymetery.;Oxygen saturation. Timepoint: before spinal anesthesia andevery 5 minutes interval through out the surgery until 30 minutes,therefore at 15minutes interval until 1.5 hourrs after spinal. Method of measurement: palse oxymetery.	—

Measure

Time frame

Blood pressure. Timepoint: before spinal anesthesia andevery 5 minutes interval through out the surgery until 30 minutes,therefore at 15minutes interval until 1.5 hourrs after spinal. Method of measurement: palseoxymetery.;Heart rate. Timepoint: before spinal anesthesia andevery 5 minutes interval through out the surgery until 30 minutes,therefore at 15minutes interval until 1.5 hourrs after spinal. Method of measurement: palseoxymetery.;Oxygen saturation. Timepoint: before spinal anesthesia andevery 5 minutes interval through out the surgery until 30 minutes,therefore at 15minutes interval until 1.5 hourrs after spinal. Method of measurement: palse oxymetery.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactCobra Noorian

Shahrekord University of Medical Sciences

noorian@skums.ac.ir; cobranori@yahoo.com+98 38 1333 5648

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026