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The effect of tight control acidosis vs.non tight control acidosis on early kidney function after kidney transplantation

The effect of tight control acidosis vs. non tight control acidosis on early kidney function after kidney transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138902163829N2
Enrollment
108
Registered
2011-01-14
Start date
2010-08-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Evaluation of tight control acidosis in early renal function. Surgical operation with transplant of whole organ

Interventions

Intervention 1: non tight control of acidosis in control group means when acidosis be dangerous for patient by hemodynamic instability or BE>-15 and Bicarb-15 and Bicarb<10 intervention with administ
tight control of acidosis means with sereal ABG metabolic acidosis regardless of patient hemadynamic stability is treated with Bicarbonate sodum up to BE<-5 with control of etco2 and pco2

Sponsors

Tehran University of Medical Sciences and Health Services
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age between 18 and 65 Exclusion criteria: K more than 5.5, presence of chronic liver or pulmonary disease or heart failure (EF<30%), prolonged cold or warm ischemia, dysfunction of anastomosis, re-bleeding, any complications of surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum level of creatinine. Timepoint: daily. Method of measurement: Laboratory test.;Urine volume. Timepoint: 6 hours and 24 hours postoperative. Method of measurement: Measuring the urine output in cc.

Secondary

MeasureTime frame
Serum level of Urea. Timepoint: daily. Method of measurement: laboratory test.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026