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Intravitreal bevacizumab(Avastin) for macular edema secondary to uveitis: 1 year results of a prospective pilot study

Intravitreal bevacizumab(Avastin) for macular edema secondary to uveitis: 1 year results of a prospective pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138902113846N1
Enrollment
30
Registered
2014-06-07
Start date
2013-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular edema secondary to uveitis. Other specified retinal disorders

Interventions

intra vitreal injection of bevacizomab(avastin).
Treatment - Surgery
intra vitreal injection of bevacizomab(avastin)

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: In a prospective clinical trial consecutive 30 patients with uveitis and CME will be enroll in the study. None of the patients will have a systemic or an ocular disease other than the one causing uveitis. Patients with history of other diseases causing macular edema (such as diabetes mellitus and retinal vein occlusions) will be excluded from the study. All of the patients should have decreased vision due to Cystoid Macular Edema (CME),

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Central macular thickness. Timepoint: Before injection and 1, 3, 6 and 12 months after injection. Method of measurement: SD-OCT.;Best corrected visual acuity. Timepoint: Before injection and 1, 3, 6 and 12 months after injection. Method of measurement: Standard snelen chart and log mar.

Secondary

MeasureTime frame
Complication of intravitreal injection of bevacizumab. Timepoint: During 1 year after injection. Method of measurement: Routine physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hooman Razmi

Shiraz University of Medical Sciences

hooman2482@gmail.com+98 71 1627 1382

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026