Comparison of Fast track with routine regimen in reducting postoperative thoracotomy pain and respiratory complications

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT138902093831N1

Enrollment

Registered

2010-10-09

Start date

2010-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign and Malignant disease of the lung, reduction of operative complications with regional anesthesia.

Interventions

Intervention 1: Bupivacaine 0.25% + Fentanil (1mg per hour) for 3 days after thoracotomy via epidural catheter. Intervention 2: Morphine (1mg per hour intravenous + Intercostal block with marcaine 0

Treatment - Drugs

Morphine (1mg per hour intravenous + Intercostal block with marcaine 0.25% for 3 days

Bupivacaine 0.25% + Fentanil (1mg per hour) for 3 days after thoracotomy via epidural catheter

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Both genders of patients with pulmonary disease which treated with elective thoracotomy, absence of blood coagulopathy, class I, II, or III American society of Anesthesiology, no underlying disease (pneumonia, Bronchitis, Asthma) Exclusion criteria: class IV, V ASA, FE less than 40%, patients with Aortic stenosis, intraoperative bleeding more than 25% that needed blood transfusion, Time of Surgery more than three hours

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post-thoracotomy pain. Timepoint: Daily until one week after surgery. Method of measurement: Respiratory postoperative pain and clinical symptom and signs (Pain seeing measurement).;ICU needed. Timepoint: Daily until one week after surgery. Method of measurement: Respiratory postoperative pain and clinical symptom.;Mechanical ventilation needed. Timepoint: Daily until one week after surgery. Method of measurement: Respiratory postoperative pain and clinical symptom.;Respiratory complications. Timepoint: Daily until one week after surgery. Method of measurement: Respiratory postoperative pain and clinical symptom.	—

Measure

Time frame

Post-thoracotomy pain. Timepoint: Daily until one week after surgery. Method of measurement: Respiratory postoperative pain and clinical symptom and signs (Pain seeing measurement).;ICU needed. Timepoint: Daily until one week after surgery. Method of measurement: Respiratory postoperative pain and clinical symptom.;Mechanical ventilation needed. Timepoint: Daily until one week after surgery. Method of measurement: Respiratory postoperative pain and clinical symptom.;Respiratory complications. Timepoint: Daily until one week after surgery. Method of measurement: Respiratory postoperative pain and clinical symptom.

—

Secondary

Measure	Time frame
Mortality. Timepoint: Daily until one week. Method of measurement: Death rate.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Sokouti

Cardiothoracic Surgery Department

Sokoutim@tbzmed.ac.irBabak756a@yahoo.com+98 41 1336 6634

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026