hyperlipidemia. Hyperlipidaemia, unspecified
Conditions
Interventions
Intervention 1: Administration of grape seed extract in cases groop and estimated paraoxonase activity before and 8 weeks after intervention. Intervention 2: Administration of placebo in control grou
Treatment - Drugs
Administration of grape seed extract in cases groop and estimated paraoxonase activity before and 8 weeks after intervention
Administration of placebo in control group and estimated of paraoxonase activity before and 8 weeks after intervention
Sponsors
Tabriz University of Medical Science-Drug Applied Research Center
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: healthy adults with TG> 150 mg / dl and T.chol> 200mg/dl and had to be willing to cooperate. Exclusion Criteria: 1. Severe hyperlipidemia 2.Treatment by Hyperlipidemic drugs or other drugs (two months before) 3. Consumption of vegetarian diets 4. Alcoholism 5. Kidney or heart failure 6. Malignant disease 7. BMI> 30 kg/m2 8. Chronic liver disease (transaminase two times more than normal) 9. Diabetes 10. Smoking and Tobacco
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lipid profile changes in hyperlipidemic pathients. Timepoint: Before and 8 week after intervention. Method of measurement: Spectrophotometric method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the PON activity. Timepoint: Before and 8 week after intervention. Method of measurement: Spectrophotometric method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Amir Ghorbanihaghjo
Tabriz University of Medical Science-Drug Applied Research Center
Outcome results
None listed