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Patient Controlled Analgesia for Total Hip or Knee Arthroplasty

Comparison of interavenous patient controlled analgesia and epidural patient controlled analgesia methods after knee or hip arthroplasty operations in Ayatollah Kashani hospital -Isfahan

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138902023771N1
Enrollment
60
Registered
2010-06-15
Start date
2010-06-24
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post hip or knee arthroplasty surgery pain. Adjustment and management of infusion pump

Interventions

Intervention 1: Intervention group: Epidural PCA( Analgesic Solution (marcaine 0.0625 -0.125% -fentanil 5ug/ml), continuos Rate (ml/hr): 4-10-Demand Dose (ml): 3-4-Lokout Interval: 10-15min) for 24 h
Treatment - Devices
Intervention group: Epidural PCA( Analgesic Solution (marcaine 0.0625 -0.125% -fentanil 5ug/ml), continuos Rate (ml/hr): 4-10-Demand Dose (ml): 3-4-Lokout Interval: 10-15min) for 24 hours)+ 150 cc no
Control group: Intravenous PCA (Morphine 1mg/ml-Size of bolus: 0.5-2.5mg- Lockout Interval (min): 5-10min- Contionuos Infusion: 0.01-0.3mg/kg/hr) for 24 hours)+ 150 cc normal saline via Epidural PCA p

Sponsors

Vice Chancellor for Research & Technology, Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria of the study :patients that are in the range of 40-80 years ,have 1-3 ASA ,are candidates of hip or knee replacement surgery & sign the consent form. Non inclusion criteria:patients that have contraindication for regional anesthesia or coagulopathy ,platelet count less than 100000 or chronic renal failure (G.F.R<60),and narcotic addiction . Exclusion criteria : Incomplete regional anesthesia, change to spinal anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Postoperative pain. Timepoint: 0, 6, 12, and 24 hours after operation. Method of measurement: Visual analogue Scale.;Level of Conciousness. Timepoint: 0, 6, 12, and 24 hours after operation after recovery room enterance. Method of measurement: A 4 point likert scale.;Pulse rate. Timepoint: 0, 6, 12, and 24 hours after operation. Method of measurement: pulse oximeter.;Blood pressure. Timepoint: 0, 6, 12, and 24 hours after operation. Method of measurement: oscillometer.;Hypoxia. Timepoint: postoperative within 24 hours of surgery. Method of measurement: pulse oximeter.—

Secondary

MeasureTime frame
Urinary retention. Timepoint: postoperative within 24 hours of surgery. Method of measurement: using checklist.;Pruritus. Timepoint: postoperative within 24 hours of surgery. Method of measurement: using checklist.;Vomitting and Nausea. Timepoint: postoperative within 24 hours of surgery. Method of measurement: using checklist.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahtab AghaKarimi

Isfahan University of Medical Sciences

mahtabaghakarimi@yahoo.com+98 31123300917

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026