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Pentoxifylline effect in reduction of serum C-Reactive Protein (CRP) level in hemodialysis patients

Assessment of Pentoxifylline effect in reduction of serum C-Reactive Protein (CRP) level in hemodialysis patients in Booali Sina's hemodialysis center

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT138901293744N1
Enrollment
66
Registered
2010-06-20
Start date
2009-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

?End Stage Renal Disease. ?End Stage Renal Disease

Interventions

Intervention 1: Pentoxifylline tablet 400 mg/daily for 4 months in intervention group. Intervention 2: Pacebo tablet /daily for 4 months in control group.
Treatment - Drugs
Placebo
Pentoxifylline tablet 400 mg/daily for 4 months in intervention group
Pacebo tablet /daily for 4 months in control group

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: hemodialysis patients with ESRD (?End Stage Renal Disease) in Booali Sina's hemodialysis center. Exclusion criteria: history of Hypersensitivity to Pentoxifylline, Xanthines (eg, caffeine, theophylline), or any component of the formulation; recent cerebral and/or retinal hemorrhage; inflamatory situations (such as connective tissue Dis., diabetic foot and other vascular problems, active infections, malignancies, recent traumas, wounds and surgeries); and take any anti-inflamatory drugs in 2 months prior to trial.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum CRP. Timepoint: Before intervention and four months later. Method of measurement: mg/liter with lab-kit(nephlometry).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mahmood Ali Keshavarz

Qazvin University of Medical Sciences

keshavarz.2008@gmail.com+98 28 1333 2930

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026