Increase in pregnancy rate of infertile couples

The effect of luteal phase support by a progestogen drug (cyclogest)on pregnancy rates of stimulated IUI cycles of 98 infertile couples (study group) with unexplained infertility that were compaired with stimulated IUI cycles of 102 infertile couples (control group) without drug taking for luteal phase support

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT138901283737N1

Enrollment

200

Registered

2010-04-28

Start date

2007-09-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility. Female infertility

Interventions

Intervention 1: in study group:Cyclogest/400 mg every night/in luteal phase/ if pregnancy happen, this drug will continue till 10 weeks/ if pregnancy does not happen, the drug will continue till14 nig

Treatment - Drugs

in study group:Cyclogest/400 mg every night/in luteal phase/ if pregnancy happen, this drug will continue till 10 weeks/ if pregnancy does not happen, the drug will continue till14 nights.

in control group: no drug receiving in luteal phase.

Eligibility

Sex/Gender

All

Age

18 Years to 36 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:infertile couples with unexplained infertility / normal semen analysis based on World Health Organization criteria /normal early follicular phase ultrasound / normal FSH and LH (20 nmol/L/patent tubes and normal uterine cavity confirmed with hysterosalpingography. The unexplained infertile patients were excluded from the study if the female partners had age> 36 years old, diminished ovarian reserve (basal FSH level>10 IU/ L), one ovary, polycystic ovaries on ultrasound examination, previous surgery on ovaries, endometriosis and any type of endocrine diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pregnancy rate. Timepoint: monthly. Method of measurement: pregnancy rate persentile/ pregnancy will be confirmed by serum sample test.	—

Secondary

Measure	Time frame
Live birth rate. Timepoint: 9 months. Method of measurement: live birth rate persentile in each groups.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFiroozeh Akbari M.D

Tehran Medical Sciences University

f.asbagh@razi.tums ac ir/maeb214@yahoo.com/f. asbaghM.D@yahoo.com+98 21 8889 7761

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026