Diabetes mellitus. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group: capsule contains 100 mg of hydro alcoholic extract of Juglans regia leaves, twice daily for 8 weeks. Intervention 2: Placebo group: flour of bean capsul, twice dail
Treatment - Drugs
Placebo
Intervention group: capsule contains 100 mg of hydro alcoholic extract of Juglans regia leaves, twice daily for 8 weeks
Sponsors
Mazandaran University of Medical Sciences and Health Services
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 30 to 80, HbA1C>7% in spite of using 50% of maximal dose of two antidiabetic drug. Exclusions criteria: Immune deficiency, pregnancy and lactation, cardiovascular disease, currently receiving corticosteroids and thiazide, uncontrolled thyroid dysfunction, acute infection ,history of diabetic ketoacidosis , Cr>1.5 for male, Cr>1.2 for female, acute hepatitis, cirrhosis, proliferative retinopathy and severe weight loss (at least 10% during last 6 months)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1C. Timepoint: before and after intervention. Method of measurement: laboratory.;FBS. Timepoint: before and 4 and 8 weeks after intervention. Method of measurement: laboratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum insulin. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory.;Lipid profile. Timepoint: before and 4 and 8 weeks after intervention. Method of measurement: laboratory.;Weight. Timepoint: before and after intervention. Method of measurement: weight Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParisa Rabie
Mazandaran University of Medical Sciences and Health Services
Outcome results
None listed