ischemic stroke. Stroke
Conditions
Interventions
Intervention 1: Magnesium sulfate 4gr IV in 50 cc normal saline over 15 minutes followed by 16 gr in 100cc over 24 hours. Intervention 2: equal volumes of normal saline.
Treatment - Drugs
Placebo
Magnesium sulfate 4gr IV in 50 cc normal saline over 15 minutes followed by 16 gr in 100cc over 24 hours
equal volumes of normal saline
Sponsors
Vice-chancellor for research, Kermanshah University of Medical Sciences and Health Services
Eligibility
Sex/Gender
All
Age
40 Years to 95 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patient’s age between 40-95 years,last known well time within 12 hoursof treatment initiation . Exclusion criteria:pregnancy-coma -heart block-chronic renal impairment- respiratory distress(24 220mmhg- pre-existing neuralgic psychiatric or advanced systemic disease that confound neuralgical or functional outcome evaluation -hemorrhagic stroke - known recent stroke wheithin past 30 days- rapidly resolving deficit
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measure of global disability. Timepoint: before of the treatment ,3days after treatment and discharge time. Method of measurement: according to modified Rankin scale.;Mortality rate. Timepoint: During admition times. Method of measurement: patient' s medical documents.;Amount of admition times. Timepoint: discharge time. Method of measurement: patient' s medical documents. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical side effects. Timepoint: daily. Method of measurement: According to patients daily notes. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Dariush Afshari
Emam Reza hospital
Outcome results
None listed