general anesthesia. Other and unspecified general anaesthetics
Conditions
Interventions
Intervention 1: Injection of aminophyline, 1 mg/kg in 10 ml of distilled water, at the end of surgery when spontaneous breathing begins and propofol infusion stops. Intervention 2: Injection of 10 ml
Prevention
Placebo
Injection of aminophyline, 1 mg/kg in 10 ml of distilled water, at the end of surgery when spontaneous breathing begins and propofol infusion stops.
Injection of 10 ml of distilled water at the end of surgery when spontaneous breathing begins and propofol infusion stops.
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age of 18- 65, ASA I and II, scheduled for lower abdomen surgery, non pregnant, without any history of cardiac, pulmonary and nourologic disease, not using tranquilizers or opioids and theophyline group drugs. Exclusion criteria: hypotension during anesthesia that do not response to fluid therapy and need to decrease propofol infusion or need for using vasoactive drugs for treatment, need for more opioid during anesthesia.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recovery time. Timepoint: once. Method of measurement: time from injection of drug or placebo to release from recovery.;Extubation time. Timepoint: once. Method of measurement: time from injection of drug or placebo to extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygen saturation. Timepoint: every 2 minutes from injection of drug or placebo to extubation then every 5 minutes till release from recovery. Method of measurement: pulse oximeter.;Heart rate. Timepoint: every 2 minutes from injection of drug or placebo to extubation then every 5 minutes till release from recovery. Method of measurement: pulse oximeter.;Mean arterial pressure. Timepoint: every 2 minutes from injection of drug or placebo to extubation then every 5 minutes till release from recovery. Method of measurement: automated blood pressure recorder.;Nausea and vomiting. Timepoint: as happens. Method of measurement: diagnosed by anesthetist.;Dysrythmia. Timepoint: as happens. Method of measurement: electrocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Bijan Yazdi
Arak Univarsity of Medical Sciences
Outcome results
None listed