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The clinical evaluation of Platelet-Rich Plasma effects on Free Gingival Graft's donor site wound healing

The clinical evaluation of Platelet-Rich Plasma effects on Free Gingival Graft's donor site wound healing

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138812093451N1
Enrollment
20
Registered
2011-01-02
Start date
2010-02-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

wound healing. Superficial injury of lip and oral cavity

Interventions

Intervention 1: using growth factors (autogenous, 0.5 cc): injected around the wound by insulin syringe. Intervention 2: control group normal healing process without growth factor application.
Treatment - Drugs
using growth factors (autogenous, 0.5 cc): injected around the wound by insulin syringe
control group normal healing process without growth factor application.

Sponsors

Babol University Of Medical Scienses, Dental Material Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 20 to 45 years old, need to bilateral (left and right) Free Gingival Graft for loss of attached gingiva or high frenum or shalloe vestibular depth, Recipient site has to be about 2 cm Exclusion criteria: presence of Systemic diseases or life style elements that impact on healing process such as diabetes mellitus, Immune system diseases, history of alcohol use, healing disorders, addiction, smoking or no cooperation, abnormal CBC or blooding time

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wound healing. Timepoint: 2,4,7,14 days and second month after the surgery. Method of measurement: landry healing scale.;Pain. Timepoint: days 2, 4, 7, 14 after surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Tissue thickness. Timepoint: before intervention and 2 months after surgery. Method of measurement: with periodontal probe and in milimeter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBardia Vadiati

Babol University Of Medical Scienses

dr.bardia_vad@yahoo.com+98 11 1222 7667

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026