early menopausal complications. Menopausal and female climacteric states
Conditions
Interventions
Intervention 1: Fenugreek group: two capsules each containing 500 mg Fenugreek extract, daily. Intervention 2: Hormone therapy group: two capsuls containing estrogen conjugate 0.625mg and medroxy pro
Treatment - Drugs
Placebo
Fenugreek group: two capsules each containing 500 mg Fenugreek extract, daily
Hormone therapy group: two capsuls containing estrogen conjugate 0.625mg and medroxy progestron acetat 2.5mg, daily
Placebo group: two capsules containing lactose, daily
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: -No any menstrual bleeding experience at least during last year. -Normal blood pressure. - In evaluation of Green questionnaire, the minimum score is 15. - FSH> 40. Exclusion Criteria: -The History of known disease or abnormality (e.g, breast cancer, uterine cancer, endometrial hyperplasia, angina, heart attacks, angioplasty, blood clot, kidney disease, liver disease, thyroid disease, diabetes, migraine headaches). - Abnormal vaginal bleeding - The use of special drugs or treatments like: hormonal therapy, nervous drugs, Corticosteroids drugs and anti-clot or herbal medicine during the past 6 months. - The use of relaxation techniques during the past 6 months. - Sensitivity to spices and essential oil materials -Smoking or drinking Alcohol.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early menopausal complications. Timepoint: before intervention, fourth and eighth weeks after intervention. Method of measurement: Greene questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: fourth and eighth weeks after intervention. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Bakouei
Babol University of Medical Sciences
Outcome results
None listed