Effects of consumption of probiotic yogurt in pregnancy

Comparison of effects of consumption of probiotic and conventional yogurt on oxidative stress and serum TNF-a and CRP in pregnant women and anthropometric indices of neonates

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138811282394N3

Enrollment

100

Registered

2011-06-06

Start date

2011-03-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy. Sequelae of complication of pregnancy, childbirth and the puerperium

Interventions

Intervention 1: 200 gram probiotic yogurt daily at lunch time for 9 weeks. Intervention 2: 200 gram conventional yogurt daily at lunch time for 9 weeks.

200 gram probiotic yogurt daily at lunch time for 9 weeks

200 gram conventional yogurt daily at lunch time for 9 weeks

Eligibility

Sex/Gender

Female

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria 1- Pregnant women aged 18-30 years; 2- Willing to participate; 3- First pregnancy; Exclusion criteria: 1- Premature labor; 2- Gestational diabetes or other complications of pregnancy; 3- Having illness including cardiovascular , liver or kidney disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Total antioxidant capacity. Timepoint: at baseline, after 9 weeks. Method of measurement: colorimetric.;Glutathione peroxidase. Timepoint: at baseline, after 9 weeks. Method of measurement: spectrophotometery.;Glutathione reductase. Timepoint: at baseline, after 9 weeks. Method of measurement: spectrophotometery.;8-oxy-guanine. Timepoint: at baseline, after 9 weeks. Method of measurement: ELISA.;Tumor necrosis factor-alpha. Timepoint: at baseline, after 9 weeks. Method of measurement: ELISA.;C-reactive protein. Timepoint: at baseline, after 9 weeks. Method of measurement: ELISA.	—

Measure

Time frame

Total antioxidant capacity. Timepoint: at baseline, after 9 weeks. Method of measurement: colorimetric.;Glutathione peroxidase. Timepoint: at baseline, after 9 weeks. Method of measurement: spectrophotometery.;Glutathione reductase. Timepoint: at baseline, after 9 weeks. Method of measurement: spectrophotometery.;8-oxy-guanine. Timepoint: at baseline, after 9 weeks. Method of measurement: ELISA.;Tumor necrosis factor-alpha. Timepoint: at baseline, after 9 weeks. Method of measurement: ELISA.;C-reactive protein. Timepoint: at baseline, after 9 weeks. Method of measurement: ELISA.

—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026