phase I clinical trial of topical Carbon Selenium Complex

Identification of Maximum Tolerated Dose for topical form of Carbon Selenium Complex in healthy volunteers

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT138811253267N1

Enrollment

Registered

2010-06-12

Start date

2010-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heat burn injury. Burns and corrosions of external body surface, specified by site

Interventions

Carbn Selenium Complex oinment will be applied on anterion of forearm in a 5*5 cm surface daily for 14 days. No derressing will be needed and no washing for 6 hours will be required..

Treatment - Drugs

Carbn Selenium Complex oinment will be applied on anterion of forearm in a 5*5 cm surface daily for 14 days. No derressing will be needed and no washing for 6 hours will be required.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: signing informed consent, no extremities edema or other abnormal signs, normal lab test including: Liver function tests ( AST, ALT, Alkaline Phosphatase, and Bilirubin); serum creatinine; Random blood sugar level

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Sebum measurment. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;Hydration. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;PH. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;Pigmentation. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;Erythema. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;Trans epidermal water loss (TEWL). Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).	—

Measure

Time frame

Sebum measurment. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;Hydration. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;PH. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;Pigmentation. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;Erythema. Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).;Trans epidermal water loss (TEWL). Timepoint: at first session (before and 30 min after application), at last session. Method of measurement: by using C.K tool(courage-khazaka).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Firooz

Center for Research and Training in Skin Diseases and Leprosy

alifiruz@yahoo.com; firozali@sina.tums.ac.ir+98 21 8897 8190

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026