Effect of two different diets on non-alcoholic fatty liver disease patients

Effect of two isocaloric energy-restricted diets on non-alcoholic fatty liver disease patients: a cross over randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138811203320N1

Enrollment

Registered

2010-03-14

Start date

2009-04-14

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-alcoholic fatty liver disease. Fatty (change of) liver, not elsewhere classified

Interventions

Intervention 1: high carbohydrate diet (55%). Intervention 2: high fat diet (40%).

Lifestyle

high carbohydrate diet (55%)

high fat diet (40%)

Eligibility

Sex/Gender

All

Age

20 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Liver steatosis on sonographic image, 20-55 years old, BMI>=25, moderately activity. Exclusion criteria: Alcohol intake more than 20g/d, gestation or lactation, very active or inpatients, hypertension, Cardiovascular disease, Pulmonary disease, renal disease, liver transplantation, other liver diseases and chronic or acute liver disease(Hepatitis A,B, ...), bilious impairments, cancers, inheritance diseases, using drugs like blood pressure lowering, statins, insulin sensitivity enhancer, hepatotoxic drugs and estrogen

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Liver enzymes. Timepoint: begin and end of each phase. Method of measurement: Autoanalyser.	—

Secondary

Measure	Time frame
Liver steatosis. Timepoint: begin and end of first phase(first 6 weeks) and end of second phase(second 6 weeks). Method of measurement: Liver sonography.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026