Rheumatoid arthritis. Seropositive rheumatoid arthritis
Conditions
Interventions
Intervention 1: One placebo tablet per day for 3 months. Intervention 2: Atorvastatin oral pills 40 mg one tablet per day for 3 months. Intervention 3: Simvastatin oral pills 40 mg one tablet per day
Placebo
Treatment - Drugs
One placebo tablet per day for 3 months
Atorvastatin oral pills 40 mg one tablet per day for 3 months
Simvastatin oral pills 40 mg one tablet per day for 3 months
Sponsors
Vice chancellery of research, Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Rheumatoid arthritis patients (proved by ACR criteria) and 3 months passed from their diagnosis. Exclusion criteria: Drug reaction, lapse from the study, Immigration or death, containdications for statins (pregnancy, lactation, abnormal liver function tests abnormality
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical and laboratory findings. Timepoint: Before the study and 3 months later. Method of measurement: DAS28, ESR, VAS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Better control of rheumatoid arthritis and prevention of joint destruction. Timepoint: Befor the study and 3 months later. Method of measurement: DAS28, ESR, VAS. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMansour Salesi
Isfahan University of Medical Sciences
Outcome results
None listed