Comparison of the effect of intratracheal and intravenous lidocaine on bucking, cough, and emergence time at the end of anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138810223051N1

Enrollment

Registered

2010-06-04

Start date

2009-01-09

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Airways responses to emergence from general anesthesia. Condition 2: the emergence time. Anaesthetic, unspecified Anaesthetic, unspecified

Interventions

Intervention 1: intratracheal lidocaine 1.5 mg/kg. Intervention 2: intravenous lidocaine1.5 mg/kg.

Prevention

intratracheal lidocaine 1.5 mg/kg

intravenous lidocaine1.5 mg/kg

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: aged 18 to 60 years, scheduled for elective minor orthopedic surgery, lower abdominal surgery or gynecologic surgery Exclusion criteria: history of laryngeal or tracheal surgery or pathology, bronchial asthma, addiction and smoking., coexisting systemic illness increased intracranial pressure, severe cardiac disease, active upper respiratory tract infections, increased risk for perioperative aspiration of gastric contents, combined epidural/general anesthetic techniques, consumption of cardiovascular medications such as ACE Inhibitors

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The number of bucking and coughs. Timepoint: before tracheal extubation and thirty minutes after extubation. Method of measurement: bucking and coughing were evaluated on a 3-point scale.;The emergence time. Timepoint: the time from discontinuation of drugs to extubation of patients at awake condision. Method of measurement: In minutes.	—

Secondary

Measure	Time frame
Heart rate (HR). Timepoint: immediately after tracheal extubation. Method of measurement: with noninvasive monitoring.;Systolic blood pressure. Timepoint: immediately after tracheal extubation. Method of measurement: with noninvasive monitoring.;Diastolic blood pressure. Timepoint: immediately after tracheal extubation. Method of measurement: with noninvasive monitoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzieh-beigom Khezri

Qazvin University of Medical Sciences

mkhezri@qums.ac.irmkhezri88@gmail.com+98 28 1223 6375

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026