Medical abortion. Medical abortion
Conditions
Interventions
Intervention 1: Misoprostol, 400 mg, vaginal, every 6 hours, within 48 hours. Intervention 2: Misoprostol, 400 mg, vaginal, every 12 hours, within 48 hours.
Treatment - Drugs
Misoprostol, 400 mg, vaginal, every 6 hours, within 48 hours
Misoprostol, 400 mg, vaginal, every 12 hours, within 48 hours
Sponsors
Vice-chancellor for Research, Qazvin University of Medical Sciences and Health Services, Iran
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: pregnant women between 14 -28 weeks of gestation undergoing termination of pregnancy because of fetal anomalies, IUFD, PROM, severe Oligohydraminious, maternal diseases. Exclusion criteria: uncontrolled heart diseases, acute asthmatic attack, glaucoma, history of cesarean section more than two times or classic cesarean section, previous incision on uterus, parity>6
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interval between administeration of drug and expulsion of fetus. Timepoint: 24 hours, 48 hours after intervention. Method of measurement: Duration, in hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total dose of misoprostol administeration in termination of pregnancy. Timepoint: every 6 hours in teh first group, every 12 hours in the second group. Method of measurement: Total dose administered, in microgram. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Farideh Movahed
Vice-chancellor for Research, Qazvin University of Medical Sciences and Health Services, Iran
Outcome results
None listed