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Ketorolac and acetaminophen analgesic effect of morphine injection after surgery of the mandible

Comparition between the concomitant use of ketorolac and acetaminophen analgesic effect of morphine injection after surgery of the mandible

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT138810173018N1
Enrollment
60
Registered
2016-03-18
Start date
2015-01-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain control after surgery. Analgesics, antipyretics and anti-inflammatory drugs

Interventions

Intervention 1: The first group of morphine intravenously at a dose of 0.1mg / kg every 4 hours the second group of intravenous acetaminophen mg / kg 15 every 6 hours (20) and ketorolac injection at a
Treatment - Drugs
The first group of morphine intravenously at a dose of 0.1mg / kg every 4 hours the second group of intravenous acetaminophen mg / kg 15 every 6 hours (20) and ketorolac injection at a dose of 0.5mg /

Sponsors

Research deputy, Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: oral and maxillofacial surgery patients undergoing open surgery champy fixation technique for mandible fracture treatment; age 50-18 years old; no systemic problems; not having surgery on other organs. Exclusion criteria: any history of drug allergy to acetaminophen, ketorolac or morphine, alcohol; patients with a history of drug abuse; mental disorder patients; surgery took more than 2 hours; patients taking monoamine oxidase inhibitors (MAO inhibitors); patients who need more pain killer; history of chronic pain; psychopathic patients; surgery on other parts of the head and face and jaws and any change in the listed protocols.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain control. Timepoint: hours: 1, 2, 4, 8, 12, 24. Method of measurement: VAS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Vahid Dehghan Manshadi

Tabriz University of Medical Sciences

dr_dehqan@yahoo.com+98 41 3335 7314

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026