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Analgesic and anti pruritus effects of sucralfate ointment after hemorrhoids surgery

Formulation of sucralfate 10% ointment and evaluation of its analgesic and anti pruritus effects post hemorrhoidectomy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT138810173014N1
Enrollment
50
Registered
2010-06-14
Start date
2010-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Grade 3 and 4 internal hemorrhoids. Internal haemorrhoids without complication

Interventions

Intervention 1: Intervention group/ Sucralfate 10% ointment/ 2 times daily/ 1 cm of the ointment/ For 14 days. Intervention 2: Control group/ Vaseline without any drugs/ 1 cm of the ointment/ For 14 d
Treatment - Drugs
Intervention group/ Sucralfate 10% ointment/ 2 times daily/ 1 cm of the ointment/ For 14 days
Control group/ Vaseline without any drugs/ 1 cm of the ointment/ For 14 days 1

Sponsors

Vice chancellor for research and technology, Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: inclusion: Grade 3 and 4 hemorrhoids which need surgery based on physician diagnosis exclusion: Serious cardiovascular and pulmonary disease, anal fissure, fistula, abscess, unbearable side effects, inappropriate use or no use of the ointment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 6th, 12th, 24th hours and 2nd, 7th and 14th days after surgery. Method of measurement: Visual analogue scale.

Secondary

MeasureTime frame
Pruritus. Timepoint: 6th, 12th, 24th hours and 2nd, 7th, 14th days after surgery. Method of measurement: Qualitative: yes or no.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSayed Vahid Hejazi

Mazandaran University of Medical Sciences

sala@mazums.ac.ir; Hejazi.ph@gmail.com+98 15 1354 3083

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026