Diabetes. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: interventiona group 1: fortified doogh with 500 IU cholecalciferol per 250 mL. Intervention 2: control group: plain doogh. Intervention 3: interventional group 2: fortified doogh with
Treatment - Other
interventiona group 1: fortified doogh with 500 IU cholecalciferol per 250 mL
control group: plain doogh
interventional group 2: fortified doogh with 500IU cholecalciferol and 250mg calcium per 250 mL
Sponsors
National Nutrition and food Technology Research institute, Shahid Beheshti University of Medical Sci
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age: 30 to 50 years, Fasting blood glucose = 126 mg/dl. Exclusion criteria: Receiving vitamin D or calcium or omega-3 supplements within the last three months, On any medication which could potentially influence vitamin D metabolism (notably estrogens, and calcitonin) within the last three months, Any other concomitant disease such as renal, hepatic, and other endocrinological disorders, and malignancies, which could influence vitamin D metabolism. Receiving insulin or any change in the type and/or dose of the current hypoglycemic medications
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of Vitamin D status. Timepoint: baseline and 3 month after intervention. Method of measurement: serum level of 25OHD. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of inflammation and immunity markers. Timepoint: Baseline and 3 month after intervention. Method of measurement: serum CRP, IL-6, IgM, IgG, MPO and IL-1ß? IFN-? ? TNF-a concentrations in PBMCs culture medium.;Improvement of oxidate stress markers. Timepoint: baseline and 3 month after intervention. Method of measurement: total anti-oxidant capacity [TAC], carbonyl protein, MDA.;Improvement of bone markers. Timepoint: baseline and 3 month after intervention. Method of measurement: serum calcium, phosphor, magnesium, PTH, osteocalcin and osteopontin. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahareh Nikooyeh
National Nutrition and food Technology Research institute, Shahid Beheshti University of Medical Sci
Outcome results
None listed