Effects of glutamine and carnitine on physical fatigue and recovery after exercise

Effects of Glutamine and Carnitine supplement on physical fatigue, inflamatin factors and indicators of exertional muscle damage in football players

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138809282890N1

Enrollment

Registered

2010-06-13

Start date

2010-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physical fatigue, exertional muscle damage and some inflammatory indicators after high intensity exercise in football players.

Interventions

Intervention 1: Carnitine. Intervention 2: Glutamine. Intervention 3: Maltodextrine (placebo). Intervention 4: Carnitine + Glutamine.

Rehabilitation

Placebo

Carnitine

Glutamine

Maltodextrine (placebo)

Carnitine + Glutamine

Eligibility

Sex/Gender

Male

Age

19 Years to 23 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: - Male football players with more than 6-month training background. - Normal Homogram. Exclusion criteria: - smoking. - supplement consumer. - took drugs for a chronic disease. - Weighed less than 40 kg. - had blood hemoglobin level less than 12 g/dL. - had history of acute disease or operational condition less than 3 months ago. - donating blood less than 1 month ago.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Serum Cratine Kinase. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Unit per liter- Enzymatic method.;Serum Lactate Dehydrogenase. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Unit per liter- Enzymatic method.;Serum Aspartate Amino Transferase. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Unit per liter- Enzymatic method.;Serum Alanine Amino Transferase. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Unit per liter- Enzymatic method.;Serum Tumor necrosis alfa. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Pg / mL - ELISA.;Serum Interleukin - 6. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Pg / mL - ELISA.;Serum High sensitive C- Reactive protein. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Pg / mL - ELISA.;Muscle soreness. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Milimeter- Visual analogue scale.;Physical fatigue. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Milimeter- Visual analogue scale.;Serum Lactate. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: mg / dL - Enzymatic method.;Serum Free fatty acid. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: mmol / L - ELISA.;Plasma ammonia. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: mg / dL - Enzymatic	—

Measure

Time frame

Serum Cratine Kinase. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Unit per liter- Enzymatic method.;Serum Lactate Dehydrogenase. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Unit per liter- Enzymatic method.;Serum Aspartate Amino Transferase. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Unit per liter- Enzymatic method.;Serum Alanine Amino Transferase. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Unit per liter- Enzymatic method.;Serum Tumor necrosis alfa. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Pg / mL - ELISA.;Serum Interleukin - 6. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Pg / mL - ELISA.;Serum High sensitive C- Reactive protein. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Pg / mL - ELISA.;Muscle soreness. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Milimeter- Visual analogue scale.;Physical fatigue. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: Milimeter- Visual analogue scale.;Serum Lactate. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: mg / dL - Enzymatic method.;Serum Free fatty acid. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: mmol / L - ELISA.;Plasma ammonia. Timepoint: Before exercise and after exercise (Before Intervention and after intervention). Method of measurement: mg / dL - Enzymatic

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Javad Mohtadinia

Tabriz university of medical sciences

mohtadinia@tbzmed.ac.ir+98 41 1335 7580

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026