The effect of oral rinse Peppermint Essence (PE) in prevention of chemotherapy- induced oral mucositis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138809222846N1

Enrollment

Registered

2010-05-19

Start date

2009-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral mucositis. Other diseases of lip and oral mucosa

Interventions

Intervention 1: Intervention: 10 drops of oral rinse Peppermint Essence, tree times a day, from the first day of chemotherapy up to the fourteenth day. Intervention 2: Control: placebo.

Prevention

Placebo

Intervention: 10 drops of oral rinse Peppermint Essence, tree times a day, from the first day of chemotherapy up to the fourteenth day

Control: placebo

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: consciousness/literate/ admitted to hospital with colon or rectum cancer/ chemotherapeutic management with 5-fluorouracil / no stomatitis/ no oral disease/ no asthma/ no renal & liver disorders/ no auto immune disease and diabetes/ no fever and neutropenia/ no recieved antibiotic & narcotic analgesic/ no recieved another oral rinse /no mint family allergy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Oral mucositis. Timepoint: daily. Method of measurement: observation with a check list.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTahereh Ashktorab

Faculty of nursing , Shahid Beheshti University of Medical Sciences

t_ashktorab@sbmu.ac.ir+98 21 2222 1543

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026