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The treatment of nonartheritic anterior ischemic optic neuropathy by subtenon methylprednisolon

Posterior subtenon injection of methylprednisolon in nonartheritic anterior ischemic optic neuropathy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138809182833N1
Enrollment
40
Registered
2010-05-08
Start date
2004-05-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non artritic anterior ischemic opthic neropathy. Ischaemic optic neuropathy

Interventions

Intervention 1: single sub-tenon injection of 40 mg methyle prednisolone. Intervention 2: Simulated injection as placebo.
Treatment - Drugs
Placebo
single sub-tenon injection of 40 mg methyle prednisolone
Simulated injection as placebo

Sponsors

Vise chanceller for research, Isfahan University of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
37 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: recent onset of non arthritic anterior ischemic optic neuropathy, history of acute visual loss, optic disc edema, afferent papillary defect, andangiographic picture, no apparent other ocular or systemic disease related to the acute visual loss Exclusion criteria: presence of IOP of more than 21 mmhg, history of glaucoma, ocular hypertention, abnormal visual field in the sound eye, high ESR, any additional intervention during the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Visual acuity. Timepoint: before the intervention and at 2 weeks, 4 weeks, 6 weeks, and 8 weeks steps of follow up after the intervention. Method of measurement: Snellen chart.;Optic disc edema. Timepoint: before the intervention and at 2 weeks, 4 weeks, 6 weeks, and 8 weeks steps of follow up after the intervention. Method of measurement: Slit lamp ophthalmoscopy.

Secondary

MeasureTime frame
Plotting the visual field. Timepoint: before the intervention and at 8 weeks steps of follow up after the intervention. Method of measurement: Humphry Automated perimeter.

Countries

Iraq

Contacts

Public ContactHamid Fesharaki

Esfahan Eye Research Center

h_fesharaki@med.mui.ac.ir+98 31 1445 2033

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026