Intranasal Desmopressin spray efficacy in acute renal colic

The Efficacy of intranasal desmopressin with Intramuscular sodium diclofenac in comparison with Intramuscular sodium diclofenac alone in acute renal colic

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT138809082782N1

Enrollment

120

Registered

2014-06-06

Start date

2014-05-16

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal colic.

Interventions

Intervention 1: 40 microgram Desmopressin spray intranasal (4 puff)l with 75 mg sodium diclofenac intramuscular. Intervention 2: 75 mg sodium diclofenac intramuscular with 4 puff NACL 0.65% intranasal

Treatment - Drugs

40 microgram Desmopressin spray intranasal (4 puff)l with 75 mg sodium diclofenac intramuscular

75 mg sodium diclofenac intramuscular with 4 puff NACL 0.65% intranasal spary

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 18-55 years old ; clinical diagnosis of acute renal colic Exclusion criteria: hypertension ; coronary artery disease ; rhinitis ; influenza ; coagulopathy ; anticoagulant therapy ; peptic ulcer disease ; asthma, kidney failure ; liver failure ; pregnancy ; use of analgesics within 4 hours and Alpha blockers before admission ; addiction to drugs ; surgery on the kidney or ureter ; and fluids therapy immediately before admission ; unbearable pain ; refusion of patients of any cause

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain severity score. Timepoint: Before intervention and at 15, 30, 45 and 60 minutes after intervention. Method of measurement: Visual analuge scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKambiz Masoumi

Ahvaz Jundishapur University of Medical ScienceS

kami_masoumi@ajums.ac.ir+98 61 1222 9166

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026