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comparison of Azithromycin and Clarithromycin in H pylori eradication

comparison of Azithromycin and Clarithromycin in H pylori eradication

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT138809052777N1
Enrollment
150
Registered
2010-01-13
Start date
2008-12-14
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection. Other and unspecified infectious diseases

Interventions

Intervention 1: Azithromycin 250 mg/ bid /orally for 4 days and 250 mg/ daily/oral for additional 6 days, Amoxicillin 1 gr/bid/orally, Omeprazole 20 mg/bid/orally before meal both for 10 days. Interve
Treatment - Drugs
Azithromycin 250 mg/ bid /orally for 4 days and 250 mg/ daily/oral for additional 6 days, Amoxicillin 1 gr/bid/orally, Omeprazole 20 mg/bid/orally before meal both for 10 days
Clarithromycin 500 mg/bid/orally, Amoxicillin 1 gr/bid/orally and Omeprazole 20 mg/bid/orally before meal, for 10 days

Sponsors

Research Division of Qom University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: H pylori positive patients with endoscopically documented peptic ulcer disease, presence of erosive gastritis or duodenitis or patients with normal endoscopy but first degree relative with gastric cancer Exclusion criteria: age less than eighteen years old, gastric outlet obstructionT, history of allergy to penicillin derivatives

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Eradication of helicobacter pylori infection. Timepoint: after termination of 40 days course of treatment. Method of measurement: urease breath test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Saeid Sarkeshikian

Qom University of Medical Sciences

s-sarkeshikian@muq.ac.ir+98 25 1291 9365

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026