Study on the efficacy of nettle in the treatment of type 2 diabetic patients

Study on the Efficacy of Aerial Parts Extract of Urtica dioica L. in Treatment of Type 2 Diabetic Patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT138809022288N2

Enrollment

Registered

2009-12-12

Start date

2007-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus. Non-insulin-dependent diabetes mellitus (type 2)

Interventions

Intervention 1: Nettle aerial parts extract at the dose of one 500 mg capsule every 8 hours in addition to the oral synthetic antidiabetic drugs for 3 months. Intervention 2: one placebo capsule every

Treatment - Drugs

Placebo

Nettle aerial parts extract at the dose of one 500 mg capsule every 8 hours in addition to the oral synthetic antidiabetic drugs for 3 months

one placebo capsule every 8 hours in addition to the oral synthetic antidiabetic drugs for 3 months

Eligibility

Sex/Gender

All

Age

40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: type 2 diabetic patients, patients aged 40 to 60 years, patients with fasting serum glucose level above 200 mg/dl, patients with blood glycosylated hemoglobin level above 8 percent, patients who despite using a combination of oral synthetic antidiabetic drugs, their blood glucose level is not within the normal range and thus need insulin injection but refuse to inject insulin. Exclusion criteria:patients with cardiac, renal, hepatic diseases, concomitant infections, pregnant women, women planning pregnancy, breast-feeding women.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Decrease of the serum glucose level. Timepoint: 3 months. Method of measurement: Medical laboratory (kit).;Decrease of the blood glycosylated hemoglobin level. Timepoint: 3 months. Method of measurement: Medical laboratory (kit).	—

Secondary

Measure	Time frame
Increase of the serum creatinin level. Timepoint: 3 months. Method of measurement: Medical laboratory (kit).;Increase of the serum level of the liver enzyme SGOT. Timepoint: 3 months. Method of measurement: Medical laboratory (kit).;Increase of the srum level of the liver enzyme SGPT. Timepoint: 3 months. Method of measurement: Medical laboratory (kit).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Saeed Kianbakht

Institute of Medicinal Plants affiliated with ACECR

kianbakht@imp.ac.ir; skianbakht@gmail.com; skianbakht@hotmail.com+98 26147640109

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026