Effect of Glycyrrhiza glabra on pain and defecation of patients with irritable bowel syndrome

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT138808202696N1

Enrollment

Registered

2010-04-26

Start date

2010-01-29

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable Bowel Syndrome. ????? ???? ????? ????

Interventions

Intervention 1: Patients in case group received Glycyrrhiza glabra tablets, 2 tablets three times per day. Intervention 2: The control group received placebo instead of Glycyrrhiza glabra, 2 tablets t

Treatment - Drugs

Patients in case group received Glycyrrhiza glabra tablets, 2 tablets three times per day

The control group received placebo instead of Glycyrrhiza glabra, 2 tablets three times per day

Patients in case group received nortriptyline tablets, 1 tablet three times per day

Patients in control group received nortriptyline tablets, 1 tablet three times per day

Eligibility

Sex/Gender

All

Age

15 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion: patient with reccognized IBS with Rome III criteria, Exclusion: any bleeding, weight loss, malabsorbtion, anemia, ocult blood, high erythrocyte sedimentation rate,

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain severity. Timepoint: daily for 8 weeks. Method of measurement: QUESTIONNAIRE.;Stool hardness. Timepoint: daily for 8 weeks. Method of measurement: questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mahmoud Rafieian-Kopaei

Shahrekord Univ. of Med. Sci. Shahrekord . Iran

rafieian@yahoo.com+98 38 1334 6692

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026