The effect of Magnesium Oxide on Improvement of Carotid intima media Thickness in hemodialysis patients

The evaluation of the effect of Magnesium Oxide on Improvement of Carotid intima media Thickness in hemodialysis patients in Alzahra & Khorshid hospitals in 1388-1389

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT138808202370N4

Enrollment

Registered

2010-04-24

Start date

2009-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Stage Renal Disease. End stage renal disease

Interventions

Intervention 1: Tab Magnesium Oxide 440mg every two days for 6 months. Intervention 2: Placebo pill the same as intervention group.

Treatment - Drugs

Tab Magnesium Oxide 440mg every two days for 6 months.

Placebo pill the same as intervention group

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusions: 1- Age >= 18 2- Not having class IV heart failure 3- No history of CABG 4- No history of recent chemotherapy for malignancy 5- Serum PTH > 100 6- Serum Mg > 1.6 3 mo) 9- Not having uncontrolled HTN 10- Not being in transplantation schedule in the following 6 months Exclusions: 1- No compliance 2- Severe side effects 3- Serum Mg > 4 mg/dl 4- Transplantation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Carotid Intima Media Thickness. Timepoint: Before & After Intervention. Method of measurement: Ultrasound Scan.	—

Secondary

Measure	Time frame
Serum Ca. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum phsphorus. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum albumin. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum PTH. Timepoint: Before & After Intervention. Method of measurement: Gama Counter.;Serum magnesium. Timepoint: Before, monthly & After Intervention. Method of measurement: Autoanalyser.;Serum TG. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum total cholestrol. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum HDL. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum LDL. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum bicarbonate. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum CRP. Timepoint: befoe & after intervention. Method of measurement: ELISA.	—

Measure

Time frame

Serum Ca. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum phsphorus. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum albumin. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum PTH. Timepoint: Before & After Intervention. Method of measurement: Gama Counter.;Serum magnesium. Timepoint: Before, monthly & After Intervention. Method of measurement: Autoanalyser.;Serum TG. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum total cholestrol. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum HDL. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum LDL. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum bicarbonate. Timepoint: Before & After Intervention. Method of measurement: Autoanalyser.;Serum CRP. Timepoint: befoe & after intervention. Method of measurement: ELISA.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mojgan Mortazavi

Isfahan University of Medical Sciences

m_mortazavi@med.mui.ac.ir, mojgan520@yahoo.com+98 31 1625 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026