Chronic obstructive pulmonary disease. chronic Bronchitis, Emphysema with FEV1<70
Conditions
Interventions
Intervention 1: Placebo with dose of 200 mg every 12 hours for one month. Intervention 2: Theophylline tablets, 200 mg every 12 hours for one month.
Placebo
Treatment - Drugs
Placebo with dose of 200 mg every 12 hours for one month
Theophylline tablets, 200 mg every 12 hours for one month
Sponsors
Vice-chancellor for Research, Kurdistan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: stable COPD (no exacerbation in the past two months), FEV1/FVC ratio less than 70%. Exclusion criteria: no smoking history, FEV1 increased more than 200 cc or 12% after administration of 400 micrograms spray Salbutamol in spirometry, clinical or radiographic evidence of pneumonia, history of infectious disease such as tuberculosis, recent respiratory tract infections, bronchiectasis, acute or chronic diarrhea, rheumatoid arthritis, degenerative disease of large joint, vasculitis, and the possibility of malignancy based on history and examination and Theophylline use during a month prior to the enrollment
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HS-CRP serum levels. Timepoint: Before and after intervention. Method of measurement: ELISA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Naseh Sigari
Kurdistan University of Medical Sciences
Outcome results
None listed