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Amniotic membrane in treatment of gingival recessions

Clinical comparison between coronally advanced flap with amniotic membrane or subepithelial connective tissue grafts in treatment of Miller class ? and ?? gingival recessions.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT138808142670N1
Enrollment
30
Registered
2010-05-11
Start date
2009-09-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival recession. Gingival recession (generalized)(localized)(postinfective)(post-operative)

Interventions

Intervention 1: Coronally advanced flap with amniotic membrane. Intervention 2: Coronally advanced flap with subepithelial connective tissue graft.
Treatment - Surgery
Coronally advanced flap with amniotic membrane

Sponsors

Searching Office of Medical Sciences University
Lead Sponsor
Humapeyvandtamin company
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1) Teeth with Miller class ? and ?? gingival recessions in buccal/facial aspects which are placed in maxillary and/or mandibular canine, premolar and incisors with recession depth>=3mm 2) Sufficient vestibular depth 3) The width of keratinized gingiva for coronally advanced flap>=3mm Exclusion criteria: 1) Systemic diseases which affect the periodontioum. 2) Bleeding on probing in surgery regions. 3) Poor oral hygiene (plaque index>%20) 4) Pregnancy 5) Steroid therapy 6) Teeth with history of endodontic therapy 7) Teeth with history of root coverage surgery 8) Teeth with symptoms such as pain and sensitivity and PDL widening and periapical radiolucency in periapical radiography 9) Need for antibiotic prophylaxis 10) No written informed consent. 11) Orthodontic therapy 12) High muscle attachment and frenal pull 13) Smoking

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Root coverage. Timepoint: Baseline and first, third and sixth month following surgery. Method of measurement: Initial recession depth minus secondary recession depth divided by the initial recession depth (*100%).

Secondary

MeasureTime frame
Keratinized gingiva width. Timepoint: Baseline and first, third and sixth month following surgery. Method of measurement: The distance between gingival margin and MGJ with williams probe.;Pocket depth. Timepoint: Baseline and first, third and sixth month following surgery. Method of measurement: The distance between gingival margin and bottom of the pocket with williams probe.;Attachment level. Timepoint: Baseline and first, third and sixth month following surgery. Method of measurement: The distance between stent margin and pocket depth with williams probe.;Recession depth. Timepoint: Baseline and first, third and sixth month following surgery. Method of measurement: The distance between CEJ and gingival margin with williams probe.;Recession width. Timepoint: Baseline and first, third and sixth month following surgery. Method of measurement: Recession width in CEJ with williams probe.;MGJ position. Timepoint: Baseline and first, third and sixth month following surgery. Method of measurement: The distance between stent margin and CEJ with williams probe.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Masoome Eivazi

Department of Periodontics

masoomeeivazi@yahoo.com+98 41 1335 5963

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026