Skip to content

Effects of carbamazepine on knee osteoarthritis pain in comparison to with diclofenac

Effects of carbamazepine on knee osteoarthritis pain in comparison to with diclofenac

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT138808092651N1
Enrollment
60
Registered
2010-12-18
Start date
2002-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ostearthritis. M15,M19

Interventions

Intervention 1: Diclofenac 25 mg bid for 2 weeks. Intervention 2: Carbamazepin 50 mg bid for 3 days and then 100 mg bid until 2 weeks. Intervention 3: Placebo 1 tab bid for 2 weeks.
Treatment - Drugs
Placebo
Diclofenac 25 mg bid for 2 weeks
Carbamazepin 50 mg bid for 3 days and then 100 mg bid until 2 weeks
Placebo 1 tab bid for 2 weeks

Sponsors

Rafsanjan University of Medicsl Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 149 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: clinical diagnosis of osteoarthritis according to an internist or orthopedist visit, presence of radiographic criteria, age equal or more than 40 years, at least 3 months passed from the onset of disease, Any contradiction for prescription of Carbamazepin or Diclofenac Exclusion Criteria: not willing to continue, intolerance to drug therapy, incidence of side effects to Carbamazepin or Diclofenac

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Knee pain. Timepoint: 2 weeks. Method of measurement: Visual Analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Mirzaei

Rafsanjan University of Medical Sciences

mirzaei.dr@gmail.com+98 39 1822 0039

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026